Introduction to Surface Plasmon Resonance

نویسندگان

  • ANNA J. TUDOS
  • RICHARD B.M. SCHASFOORT
چکیده

Since its first observation by Wood in 1902 [1,2], the physical phenomenon of surface plasmon resonance (SPR) has found its way into practical applications in sensitive detectors, capable of detecting sub-monomolecular coverage. What is surface plasmon resonance? Wood observed a pattern of ‘‘anomalous’’ dark and light bands in the reflected light, when he shone polarized light on a mirror with a diffraction grating on its surface. Physical interpretation of the phenomenon was initiated by Lord Rayleigh [3], and further refined by Fano [4], but a complete explanation of the phenomenon was not possible until 1968, when Otto [5] and in the same year Kretschmann and Raether [6] reported the excitation of surface plasmons. Application of SPR-based sensors to biomolecular interaction monitoring was first demonstrated in 1983 by Liedberg et al. [7]. A historical overview of the use of the phenomenon for biosensor applications is given in Section 1.3 of this chapter. To understand the excitation of surface plasmons, let us start with a simple experiment.

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تاریخ انتشار 2017